Principal Investigator

Assistant Professor
Myriam received a B.A. in molecular biology from Princeton University, and a Ph.D. in biology from the Johns Hopkins University. She received her post-doctoral training at the Rockefeller University, working with Dr. Paul Greengard and Dr. Nathaniel Heintz. In 2011 she started her research group at MIT and the Picower and Broad Institutes. Myriam can be reached at



Research Associate
Ruth Kulicke graduated from Swarthmore College in 2007 with a B.A. and high honors in psychobiology. After graduating from Swarthmore, she worked in Dr. Paul Greengard's laboratory at the Rockefeller University as a research assistant before joining Myriam Heiman at MIT in 2011. Ruth can be reached at
Research Associate

Alice graduated from MIT in 2016 with an S.B. in Brain and Cognitive Sciences. As an undergraduate, she worked at the Heiman lab to develop therapeutic strategies targeting the mutant huntingtin protein. She is currently working as a research assistant post graduation and hopes to enter medical school in 2017. She can be reached at

Lab Manager
Scott graduated the University of New Hampshire in 1998 with a B.S. in Zoology. Afterwards he spent over 10 years as a research technician, and eventual lab manger, for the Ophthalmic Genetics Institute at the Massachusetts Eye & Ear Infirmary.  In 2010, he moved onto the Howard Hughes Medical Institute at MIT within the lab of Li-Huei Tsai.  Scott took time off to be a stay-at-home dad in 2011, but once his daughter began school in 2015, he returned to MIT joining the Heiman lab as technician and lab manager.  He can be reached at

Postdoctoral Fellows


Mary received a B.S. in biology from Boston College in 2006 where she studied nuclear import of HPV proteins with Dr. Junona Moroianu. She received her Ph.D. in neuroscience from Harvard Medical School in 2015. For her graduate work, she trained in Dr. Mustafa Sahin’s lab at Boston Children’s hospital studying the role of motor neuron-specific microRNA dysregulation in Spinal Muscular Atrophy. In the Heiman lab, she is pursuing her interest in neurodegeneration, and cell-type specific vulnerability to disease. Mary can be reached at

Hyeseung was born in Seoul, South Korea. She graduated from Seoul Science High School and received her B.S in Chemistry and Life Sciences from Ewha Womans University. Her graduate work in the Tavazoie lab at the Rockefeller University centered around the role of the SOX4 transcription factor in driving cancer metatasis as well as the role of the m6A methylation mark in regulating non-coding RNA processing. Hyeseung can be reached at    
Martine graduated from McGill University in 2009 with a B.S in Microbiology and Immunology. She obtained her M.S in  2012 and her Ph.D  in 2016 both in pathology and cell biology at the University of Montreal. She has worked with Drs. Guy Rouleau and Alex Parker to develop Drosophila and C. elegans models of neurodegenerative disorders caused by repeat expansions. She joined the Heiman lab in spring of 2016 and is using pluripotent stem cells to understand medium spiny neurons neurobiology and for in vitro disease modeling. Martine can be reached at

Graduate Students

Grad Student
Lea graduated from Harvard University in 2012 with a B.A. and highest honors in neurobiology. As an undergraduate, she studied the role of inhibitory interneurons in the progression of Rett Syndrome with Dr. Fagiolini and Dr. Hensch at Boston Children's Hospital/Harvard Medical School. She is now a graduate student in Brain and Cognitive Sciences at MIT and joined the Heiman lab in the spring of 2013.  Lea can be reached at

Grad Student

Amanda graduated from Brown University in 2012 with a ScB and honors in neuroscience.  As an undergraduate, she studied the role of KCNQ1 and hERG potassium channels in the context of Long QT Syndrome with Dr. Gideon Koren at the Cardiovascular Research Center.  Subsequently, Amanda worked in Professor Tyler Jacks' lab at MIT to characterize a novel mouse model of anaplastic thyroid cancer.  She joined MIT's department of Brain and Cognitive Sciences as a graduate student in the fall of 2014 and the Heiman lab in the spring of 2015 and is currently working to better understand the cellular effects of antipsychotic treatment.  Amanda can be reached at