Publications

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The Stress-Induced Atf3-Gelsolin Cascade Underlies Dendritic Spine Deficits in Neuronal Models of Tuberous Sclerosis Complex

Duyu Nie, Zehua Chen, Darius Ebrahimi-Fakhari, Alessia Di Nardo, Kristina Julich, Victoria K. Robson, Yung-Chih Cheng, Clifford J. Woolf, Myriam Heiman, Mustafa Sahin

J Neurosci. 2015 July 29; 35(30): 10762–10772.  doi: 10.1523/JNEUROSCI.4796-14.2015

PMCID: PMC4518051

 

Protein kinase A directly phosphorylates metabotropic glutamate receptor 5 to modulate its function

Ken Uematsu, Myriam Heiman, Marina Zelenina, Júlio Padovan, Brian T. Chait, Anita Aperia, Akinori Nishi, Paul Greengard

J Neurochem. Author manuscript; available in PMC 2016 March 4.Published in final edited form as: J Neurochem. 2015 March; 132(6): 677–686. Published online 2015 March 4.  doi: 10.1111/jnc.13038

PMCID: PMC4359654

 

Synthetic lethal screening in the mammalian central nervous system identifies Gpx6 as a modulator of Huntington’s disease

Reut Shema, Ruth Kulicke, Glenn S. Cowley, Rachael Stein, David E. Root, Myriam Heiman

Proc Natl Acad Sci U S A. 2015 January 6; 112(1): 268–272.  Published online 2014 December 22. doi: 10.1073/pnas.1417231112

PMCID: PMC4291668

 

Nitric oxide regulates synaptic transmission between spiny projection neurons

Yotam Sagi, Myriam Heiman, Jayms D. Peterson, Sergei Musatov, Mariangela Scarduzio, Stephen M. Logan, Michael G. Kaplitt, Dalton J. Surmeier, Nathaniel Heintz, Paul Greengard

Proc Natl Acad Sci U S A. 2014 December 9; 111(49): 17636–17641.  Published online 2014 November 20. doi: 10.1073/pnas.1420162111Correction in: Proc Natl Acad Sci U S A. 2015 April 7; 112(14): E1811.

PMCID: PMC4267338

 

Cell type-specific plasticity of striatal projection neurons in parkinsonism and L-DOPA-induced dyskinesia

Tim Fieblinger, Steven M. Graves, Luke E. Sebel, Cristina Alcacer, Joshua L. Plotkin, Tracy S. Gertler, C. Savio Chan, Myriam Heiman, Paul Greengard, M. Angela Cenci, D. James Surmeier

Nat Commun. Author manuscript; available in PMC 2015 May 14.Published in final edited form as: Nat Commun. 2014; 5: 5316. Published online 2014 October 31.  doi: 10.1038/ncomms6316

PMCID: PMC4431763

 

Cell-Type-Specific mRNA Purification by Translating Ribosome Affinity Purification (TRAP)

Myriam Heiman, Ruth Kulicke, Robert J. Fenster, Paul Greengard, Nathaniel Heintz

Nat Protoc. Author manuscript; available in PMC 2014 November 1.Published in final edited form as: Nat Protoc. 2014; 9(6): 1282–1291. Published online 2014 May 8.  doi: 10.1038/nprot.2014.085

PMCID: PMC4102313

 

Molecular adaptations of striatal spiny projection neurons during levodopa-induced dyskinesia

Myriam Heiman, Adrian Heilbut, Veronica Francardo, Ruth Kulicke, Robert J. Fenster, Eric D. Kolaczyk, Jill P. Mesirov, Dalton J. Surmeier, M. Angela Cenci, Paul Greengard

Proc Natl Acad Sci U S A. 2014 March 25; 111(12): 4578–4583.  Published online 2014 March 5. doi: 10.1073/pnas.1401819111

PMCID: PMC3970487

 

Differential effects of cocaine on histone posttranslational modifications in identified populations of striatal neurons

Emmanuelle Jordi, Myriam Heiman, Lucile Marion-Poll, Pierre Guermonprez, Shuk Kei Cheng, Angus C. Nairn, Paul Greengard, Jean-Antoine Girault

Proc Natl Acad Sci U S A. 2013 June 4; 110(23): 9511–9516.  Published online 2013 May 20. doi: 10.1073/pnas.1307116110

PMCID: PMC3677456

 

IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death during endoplasmic reticulum stress

Alana G. Lerner, John-Paul Upton, P.V.K. Praveen, Rajarshi Ghosh, Yoshimi Nakagawa, Aeid Igbaria, Sarah Shen, Vinh Nguyen, Bradley J. Backes, Myriam Heiman, Nathaniel Heintz, Paul Greengard, Simon Hui, Qizhi Tang, Ala Trusina, Scott A. Oakes, Feroz R. Papa

Cell Metab. Author manuscript; available in PMC 2014 May 8.Published in final edited form as: Cell Metab. 2012 August 8; 16(2): 250–264.  doi: 10.1016/j.cmet.2012.07.007

PMCID: PMC4014071

 

Strain-Specific Regulation of Striatal Phenotype in Drd2-eGFP BAC Transgenic Mice

C. Savio Chan, Jayms D. Peterson, Tracy S. Gertler, Kelly E. Glajch, Ruth E. Quintana, Qiaoling Cui, Luke E. Sebel, Joshua L. Plotkin, Weixing Shen, Myriam Heiman, Nathaniel Heintz, Paul Greengard, D. James Surmeier

J Neurosci. Author manuscript; available in PMC 2013 January 4.Published in final edited form as: J Neurosci. 2012 July 4; 32(27): 9124–9132.  doi: 10.1523/JNEUROSCI.0229-12.2012

PMCID: PMC3461272

 

Application of BACarray for comparative analysis of CNS cell types

Joseph P. Doyle, Joseph D. Dougherty, Myriam Heiman, Eric F. Schmidt, Tanya R. Stevens, Guojun Ma, Sujata Bupp, Prerana Shrestha, Rajiv D. Shah, Martin L. Doughty, Shiaoching Gong, Paul Greengard, Nathaniel Heintz

Cell. Author manuscript; available in PMC 2009 October 19.Published in final edited form as: Cell. 2008 November 14; 135(4): 749–762.  doi: 10.1016/j.cell.2008.10.029Correction in: volume 139 on page 1022

PMCID: PMC2763427

 

Development of a BACarray translational profiling approach for the molecular characterization of CNS cell types

Myriam Heiman, Anne Schaefer, Shiaoching Gong, Jayms Peterson, Michelle Day, Keri E. Ramsey, Mayte Suárez-Fariñas, Cordelia Schwarz, Dietrich A. Stephan, D. James Surmeier, Paul Greengard, Nathaniel Heintz

Cell. Author manuscript; available in PMC 2009 June 16.Published in final edited form as: Cell. 2008 November 14; 135(4): 738–748.  doi: 10.1016/j.cell.2008.10.028

PMCID: PMC2696821

 

Regulation of Alzheimer's disease amyloid-β formation by casein kinase I

Marc Flajolet, Gen He, Myriam Heiman, Angie Lin, Angus C. Nairn, Paul Greengard

Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4159–4164.  Published online 2007 February 27. doi: 10.1073/pnas.0611236104

PMCID: PMC1820725